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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1640510Generated: November 1, 2026

HCID 25117162, compound → HCID 66736904, compound

https://huagongshe.com/reaction/1640510

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 25117162HCID 25117162—
CatalystManganese dioxideHCID 14801—
SolventDichloromethaneHCID 6344—
ProductHCID 66736904HCID 6673690446%

Reaction Steps

A solution of the compound of Example 61 (0.55 g, 0.12 mmol) in DCM (5 mL) was treated with MnO2 (0.5 g, 50 eq.). The mixture was stirred at rt for 1 h, filtered over MgSO4 and concentrated. Chromatography on SiO2 (EA) gave the title compound as a colourless oil (0.025 g, 46% yield).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08114867B2
Source datasetuspto-grants-2012_02
ORD IDord-a0ce63213c0142b6b95bc3e008497c7a
Source noteuspto-grants-2012_02