HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 25117162, compound → HCID 66736904, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 25117162 | HCID 25117162 | — |
| Catalyst | Manganese dioxide | HCID 14801 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 66736904 | HCID 66736904 | 46% |
Reaction Steps
A solution of the compound of Example 61 (0.55 g, 0.12 mmol) in DCM (5 mL) was treated with MnO2 (0.5 g, 50 eq.). The mixture was stirred at rt for 1 h, filtered over MgSO4 and concentrated. Chromatography on SiO2 (EA) gave the title compound as a colourless oil (0.025 g, 46% yield).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08114867B2 |
| Source dataset | uspto-grants-2012_02 |
| ORD ID | ord-a0ce63213c0142b6b95bc3e008497c7a |
| Source note | uspto-grants-2012_02 |