1,4-Dioxane → Tert-butyl 2-carbamothioylpiperidine-1-carboxylate

HRID 164061Notes

Reaction equation

HRID 164061 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH:9]([C:14]([NH2:15])=[O:16])[CH2:10][CH2:11][CH2:12][CH2:13]1.[CH3:17][O:18][c:19]1[cH:20][cH:21][c:22]([P:23]2(=[S:26])[S:24][P:25]([c:27]3[cH:28][cH:29][c:30]([O:31][CH3:32])[cH:33][cH:34]3)(=[S:35])[S:36]2)[cH:37][cH:38]1.[O:39]1[CH2:40][CH2:41][O:42][CH2:43][CH2:44]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH:9]([C:14]([NH2:15])=[S:26])[CH2:10][CH2:11][CH2:12][CH2:13]1

Participants

4

Reactant 3

HCID 312751,4-DioxaneHCID 87949Lawesson's reagentHCID 2756820tert-Butyl 2-carbamoylpiperidine-1-carboxylate

Product 1

HCID 11390900Tert-butyl 2-carbamothioylpiperidine-1-carboxylate

Sources & evidence

ORD record
ord-ca14bc15440540f6b89cc79522cb353d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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