7-(Trifluoromethyl)-1H-indole → 2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-YL)-7-(trifluoromethyl)-1H-indole

HRID 1640631노트

반응식

HRID 1640631 반응식
Cl[C:2]1[CH:3]=[CH:4][CH:5]=[C:6]2[C:10]=1[NH:9][C:8]([B:11]1[O:15][C:14]([CH3:17])([CH3:16])[C:13]([CH3:19])([CH3:18])[O:12]1)=[CH:7]2.[F:20][C:21]([F:32])([F:31])C1C=CC=C2C=1NC=C2>>[F:20][C:21]([F:32])([F:31])[C:2]1[CH:3]=[CH:4][CH:5]=[C:6]2[C:10]=1[NH:9][C:8]([B:11]1[O:15][C:14]([CH3:17])([CH3:16])[C:13]([CH3:19])([CH3:18])[O:12]1)=[CH:7]2

참가 물질

3

반응물 2

HCID 104198827-(Trifluoromethyl)-1H-indoleHCID 532172117-Chloro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-YL)-1H-indole

생성물 1

HCID 569732632-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-YL)-7-(trifluoromethyl)-1H-indole

실험 절차

Prepared according to a procedure analogous to that described for 7-chloro-2-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-indole using 7-trifluoromethyl-1H-indole.

후처리

  1. customPrepared

출처 및 근거

ORD 기록
ord-2cfad68e45db4739a815fad7cedcd242
출처 데이터셋
uspto-grants-2012_02
특허 번호
US08114846B2

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