HCID 66738448, compound → HCID 66738357, compound

Participants

Reaction Steps

Stir a mixture of 2-(2-(4-(iodomethyl)-1H-1,2,3-triazol-1-yl)ethyl) isoindoline-1,3-dione (1 g, 2.62 mmol) and 0.2 g of 10% palladium on carbon in ethanol (10 mL) under a hydrogen balloon overnight. Filter to remove the solid and concentrate. Purify by column chromatography (DCM to 20% ethyl acetate in DCM) to afford the title compound as a yellow solid (0.5 g, 74%). MS (EI) m/z 257 [M+1]+.

Provenance & Evidence