Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Water | HCID 962 | — |
| Reactant | 5-Fluoro-2-nitrobenzamide | HCID 18668165 | — |
| Reactant | HCID 178527445 | HCID 178527445 | — |
| Solvent | Dimethyl Sulfoxide | HCID 679 | — |
| Product | HCID 66735912 | HCID 66735912 | 85.3% |
Reaction Steps
5-Fluoro-2-nitro-benzamide (2.5 g, 13.59 mmol) in DMSO (40 mL) was treated with solid 97% PhSO2Na (2.48 g, 14.95 mmol) and heated at 50° C. (oil bath temperature) for 60 hours. The reaction was added dropwise into 40 mL of iced water. Filtration of the solid afforded 3.55 g (85% yield) of title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US08114865B2 |
|---|
| Source dataset | uspto-grants-2012_02 |
|---|
| ORD ID | ord-468d228a0acc48849718e2c95a630729 |
|---|
| Source note | uspto-grants-2012_02 |
|---|
