Methanol → HCID 66737151, compound

Participants

Reaction Steps

The crude 2,2,2-Trifluoro-N-[5-(3-fluoro-benzenesulfonyl)-1-trityl-1H-indazol-3-yl]-acetamide (46.33 mmol) was treated with methanol (250 mL) and triethylamine (20 mL) and heated to reflux for 36 hours. The volatiles were partially evaporated, cooled and filtered. The solid was washed with a small volume of methanol then with water. After drying under vacuum at 70° C. and further purification by recrystallization from ethyl acetate the title compound was obtained as a white solid.

Provenance & Evidence