HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonium Chloride → 1-Azabicyclo[2.2.1]heptan-4-ylmethanamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonium Chloride | HCID 25517 | — |
| Reactant | Ethyl 1-azabicyclo[2.2.1]heptane-4-carboxylate | HCID 15663604 | — |
| Reactant | Trimethylaluminum | HCID 16682925 | — |
| Reactant | Aluminium lithium hydride | HCID 21226445 | — |
| Product | 1-Azabicyclo[2.2.1]heptan-4-ylmethanamine | HCID 55290190 | — |
Reaction Steps
1-Azabicyclo[2.2.1]heptan-4-ylmethanamine was prepared by treatment of ethyl 1-azabicyclo[2.2.1]heptane-4-carboxylate with ammonium chloride and trimethylaluminum and reducing the resulting amide with lithium aluminum hydride.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08114891B2 |
| Source dataset | uspto-grants-2012_02 |
| ORD ID | ord-a86dc073bb784a24b75d70f6d896622e |
| Source note | uspto-grants-2012_02 |