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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1641006Generated: November 1, 2026

6-(Difluoromethoxy)-1H-indole → 6-(difluoromethoxy)-1H-indole-3-carboxylic acid

https://huagongshe.com/reaction/1641006

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6-(Difluoromethoxy)-1H-indoleHCID 53844630—
Reactant5-(difluoromethoxy)-1H-indole-3-carboxylic acidHCID 57646514—
Product6-(difluoromethoxy)-1H-indole-3-carboxylic acidHCID 57646513—

Reaction Steps

Prepared as for 5-(difluoromethoxy)-1H-indole-3-carboxylic acid starting with 6-difluoromethoxyindole (WO 97/45408 A1). MS (m/e) 227.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08114891B2
Source datasetuspto-grants-2012_02
ORD IDord-f340e35c05c9466290faeb999e7b0877
Source noteuspto-grants-2012_02