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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1641009Generated: November 1, 2026

(Quinuclidin-4-yl)methyl 1H-indole-3-carboxylate → Quinuclidin-4-ylmethyl 5-chloro-1H-indole-3-carboxylate

https://huagongshe.com/reaction/1641009

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(Quinuclidin-4-yl)methyl 1H-indole-3-carboxylateHCID 25234267—
Reactant5-chloro-1H-indole-3-carbonyl chlorideHCID 57956866—
ProductQuinuclidin-4-ylmethyl 5-chloro-1H-indole-3-carboxylateHCID 25234271—

Reaction Steps

Quinuclidin-4-ylmethyl 5-chloro-1H-indole-3-carboxylate was prepared in a similar manner to (Quinuclidin-4-yl)methyl 1H-indole-3-carboxylate, substituting 5-chloro-1H-indole-3-carbonyl chloride as the electrophile.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08114891B2
Source datasetuspto-grants-2012_02
ORD IDord-9bef965f17314a20992deb184182d588
Source noteuspto-grants-2012_02