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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 164103Generated: October 25, 2026

Acetic Acid → N-[2-hydroxy-5-[1-hydroxy-2-[2-[4-[[1-(4-piperidin-1-ylsulfonylphenyl)piperidin-4-yl]amino]phenyl]ethylamino]ethyl]phenyl]methanesulfonamide

https://huagongshe.com/reaction/164103

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAcetic AcidHCID 176—
ReactantMethanolHCID 887—
ReactantSodium ionHCID 923—
ReactantAcetonitrileHCID 6342—
ReactantDichloromethaneHCID 6344—
ReactantTrichloromethylsilaneHCID 6399—
ReactantIodide IonHCID 30165—
ReactantCyano-borohydrideHCID 498716—
ReactantN-[5-(2-amino-1-hydroxyethyl)-2-hydroxyphenyl]methanesulphonamideHCID 9837752—
ReactantN-[4-(2,2-Dimethoxyethyl)phenyl]-1-[4-(1-piperidinylsulfonyl)phenyl]-4-piperidinamineHCID 18173830—
ProductN-[2-hydroxy-5-[1-hydroxy-2-[2-[4-[[1-(4-piperidin-1-ylsulfonylphenyl)piperidin-4-yl]amino]phenyl]ethylamino]ethyl]phenyl]methanesulfonamideHCID 70009477—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (9/10)
ORD IDord-5f0e2b0f7cd84d04b61a16881f81bcfd
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (9/10)