Chloroacetonitrile → 2-(4-Ethylpiperidin-1-yl)acetonitrile
Reaction equation
[CH2:1]([CH:3]1[CH2:8][CH2:7][NH:6][CH2:5][CH2:4]1)[CH3:2].Cl[CH2:10][C:11]#[N:12]>>[CH2:1]([CH:3]1[CH2:8][CH2:7][N:6]([CH2:10][C:11]#[N:12])[CH2:5][CH2:4]1)[CH3:2]Participants
3
Procedure
The title compound was prepared according to general procedure G described in Scheme 3 from 4-ethylpiperidine and 2-chloroacetonitrile. The crude solution was used directly without further purification.
Workup
- customThe crude solution was used directly without further purification
Sources & evidence
- ORD record
- ord-4ac651108a08449f8050138c52d497dc
- Source dataset
- uspto-grants-2012_02
- Patent number
- US08114894B2
Reaction notes
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