4-(Dimethylamino)phenol → 3-(4-(Dimethylamino)phenoxy)propyl acetate

HRID 1641109Notes

Reaction equation

HRID 1641109 reaction equation
[C:1]([O:4][CH2:5][CH:6](Br)[CH3:7])(=[O:3])[CH3:2].[CH3:9][N:10]([CH3:18])[C:11]1[CH:16]=[CH:15][C:14]([OH:17])=[CH:13][CH:12]=1>>[C:1]([O:4][CH2:5][CH2:6][CH2:7][O:17][C:14]1[CH:15]=[CH:16][C:11]([N:10]([CH3:18])[CH3:9])=[CH:12][CH:13]=1)(=[O:3])[CH3:2]

Participants

3

Reactant 2

HCID 221744-(Dimethylamino)phenolHCID 131292822-Bromopropyl acetate

Product 1

HCID 594186993-(4-(Dimethylamino)phenoxy)propyl acetate

Procedure

3-(4-(Dimethylamino)phenoxy)propyl acetate (47A) was prepared following a similar procedure as that described in example 39, except 2-bromopropyl acetate was used instead of 2-bromoethyl acetate and 4-(dimethylamino)phenol was used instead of 3-(dimethylamino)phenol in step 1 of example 39.

Sources & evidence

ORD record
ord-9634e6880aea414c998f86c049acbd04
Source dataset
uspto-grants-2012_02
Patent number
US08114893B2

Reaction notes

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