3,5-Dimethylpiperidine → HCID 59553104, compound

Participants

Reaction Steps

Compound is prepared from 3-fluoro-N-(4-{[2-(methylsulfonyl)pyrimidin-4-yl]oxy}-1-naphthyl)-5-morpholin-4-ylbenzamide and 3,5-dimethylpiperidine according to conditions described in general procedure C. Mp: 102-104° C.; 1H NMR (400 MHz, DMSO-d6) δ 0.76-0.88 (m, 6 H), 1.33-3.22 (m, 8 H), 3.27 (m, 4 H), 3.77 (m, 4H), 6.17 (d, J=5.5 Hz, 1H), 7.02-7.06 (m, 1 H), 7.27 (d, J=8.8 Hz, 1H), 7.41 (d, J=8.0 Hz, 1 H), 7.25-7.62 (m, 4H), 7.62-7.83 (m, 1 H), 7.99-8.01 (m, 1 H), 8.24 (d, J=5.5 Hz, 1 H), 10.47 (s, 1 H).

Provenance & Evidence