HuagongsheHuagongshe Chemistry Print Report · For research reference only
Tetrahydrofurfurylamine → HCID 59553321, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Tetrahydrofurfurylamine | HCID 253298 | — |
| Reactant | 3-fluoro-N-[4-(2-methanesulfonyl-pyrimidin-4-yloxy)-naphthalen-1-yl]-5-piperidin-1-yl-benzamide | HCID 66737969 | — |
| Product | HCID 59553321 | HCID 59553321 | — |
Reaction Steps
Compound is prepared from 3-fluoro-N-[4-(2-methanesulfonyl-pyrimidin-4-yloxy)-naphthalen-1-yl]-5-piperidin-1-yl-benzamide and C-(tetrahydrofuran-2-yl)-methylamine according to conditions described in general procedure C. 1H NMR (400 MHz, DMSO-d6) δ 1.40-1.65 (m, 10 H), 3.00-3.85 (m, 9 H), 6.327 (bs, 1 H), 6.96 (d, 1 H), 7.15 (d, 1 H), 7.38 (d, J=8.0 Hz, 1 H), 7.43 (s, 1 H), 7.54-7.60 (m, 3 H), 7.78-7.82 (m, 1 H), 7.96 (d, 1 H), 8.20 (s, 1 H), 10.41 (s, 1 H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08114873B2 |
| Source dataset | uspto-grants-2012_02 |
| ORD ID | ord-d1a88bd28d48476ea4013dae6bb8fc19 |
| Source note | uspto-grants-2012_02 |