4-Piperidinemethanol → HCID 59553454, compound

Participants

Reaction Steps

Compound is prepared from 3-fluoro-N-[4-(2-methanesulfonyl-pyrimidin-4-yloxy)-naphthalen-1-yl]-5-piperidin-1-yl-benzamide and piperidin-4-yl-methanol according to conditions described in general procedure C. 1H NMR (400 MHz, CDCl3) δ 1.05-1.14 (m, 2 H), 1.61-1.70 (m, 9 H), 2.74 (t, J=12.0 Hz, 2 H), 3.26 (t, J=5.5 Hz, 4 H), 3.45 (d, J=5.8 Hz, 2 H), 5.92 (d, J=5.5 Hz, 1 H), 6.74-6.77 (m, 1 H), 6.97 (d, J=7.6 Hz, 1 H), 7.25-7.29 (m, 2 H), 7.46-7.56 (m, 2 H), 7.87-7.89 (m, 2 H), 7.98 (d, J=7.7 Hz, 1 H), 8.22 (s, 2 H).

Provenance & Evidence