HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl 2-[(4-nitronaphthalen-1-yl)oxy]acetate → Methyl 2-((4-aminonaphthalen-1-yl)oxy)acetate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl 2-[(4-nitronaphthalen-1-yl)oxy]acetate | HCID 59553182 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | Methyl 2-((4-aminonaphthalen-1-yl)oxy)acetate | HCID 59553142 | 90.4% |
Reaction Steps
(4-Nitro-naphthalen-1-yloxy)-acetic acid methyl ester (0.90 g) and 10% Pd/C (90 mg) in MeOH (150 ml) is stirred at room temperature under 1 atmosphere of hydrogen for 4 h. The mixture is then filtered through Celite® and evaporated to dryness to provide (4-amino-naphthalen-1-yloxy)-acetic acid methyl ester (0.72 g). MS 232 (M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08114873B2 |
| Source dataset | uspto-grants-2012_02 |
| ORD ID | ord-27c2f7c47ab6475fa6347c96e2aed3a9 |
| Source note | uspto-grants-2012_02 |