1,4-Dioxa-8-azaspiro(4.5)decane → HCID 59553089, compound

Participants

Reaction Steps

Compound is prepared from N-[4-(2-chloroethoxy)-naphthalen-1-yl]-3-fluoro-5-piperidin-1-yl-benzamide and 1,4-dioxa-8-aza-spiro[4.5]decane according to conditions described in general procedure N. 1H NMR 300 MHz (CDCl3) 8.32(dd, 1H, J=1.8 and 8.7 Hz), 7.9(s, 1H), 7.83(d, 1H, J=7.8 Hz), 7.73(d, 1H, J=8.4 Hz), 7.53(m, 2H), 7.31(s, 1H), 6.99(d, 1H, J=8.4 Hz), 6.84(d, 1H, J=8.4 Hz), 6.76(d, 1H, J=11.7 Hz), 4.31(t, 2H, J=5.7 Hz), 3.97(s, 4H), 3.28(m, 4H), 3.02(t, 2H, J=6.9 Hz), 2.76(m, 4H), 1.8(t, 4H, J=5.7 Hz), 1.62-1.67(m, 6H).

Provenance & Evidence