Ethyl 4-piperidinecarboxylate → HCID 59553429, compound

Participants

Reaction Steps

Compound is prepared from N-[4-(2-chloroethoxy)-naphthalen-1-yl]-3-fluoro-5-piperidin-1-yl-benzamide and piperidine-4-carboxylic acid ethyl ester according to conditions described in general procedure N. 1H NMR 300 MHz (CDCl3) 8.31(dd, 1H, J=1.2 and 8.4 Hz), 7.88(s, 1H), 7.83(d, 1H, J=7.5 Hz), 7.73(d, 1H, J=8.1 Hz), 7.54(m, 2H), 7.31(s, 1H), 6.98(d, 1H, J=7.8 Hz), 6.84(d, 1H, J=8.4 Hz), 6.76(d, 1H, J=11.7 Hz), 4.31(t, 2H, J=5.7 Hz), 4.14(q, 2H, J=6.9 Hz), 3.28(m, 4H), 3.05(m, 2H), 2.97 (t, 2H, J=5.7 Hz), 2.24-2.32 (m, 3H), 1.64-1.97(m, 10H), 1.25(t, 3H, J=7.5 Hz).

Provenance & Evidence