4-Piperidinemethanol → HCID 59553195, compound

Participants

Reaction Steps

Compound is prepared from N-[4-(2-chloroethoxy)-naphthalen-1-yl]-3-fluoro-5-piperidin-1-yl-benzamide and 4-hydroxymethylpiperidine according to conditions described in general procedure N. 1H NMR 300 MHz (CDCl3) 8.32(dd, 1H, J=1.5 and 8.4 Hz), 7.88(s, 1H), 7.83(d, 1H, J=8.4 Hz), 7.73(d, 1H, J=8.1 Hz), 7.54(m, 2H), 7.31(s, 1H), 6.98(d, 1H, J=8.4 Hz), 6.84(d, 1H, J=7.8 Hz), 6.76(d, 1H, J=11.7 Hz), 4.32(t, 2H, J=5.7 Hz), 3.51(d, 2H, J=6.3 Hz), 3.28(m, 4H), 3.1(m, 2H), 2.99 (t, 2H, J=5.7 Hz), 2.23(dt, 2H, J=2.7 and 11.4 Hz), 1.32-1.8(m, 11H).

Provenance & Evidence