HCID 86636537, compound → 2-Deoxy-L-ribose

HRID 1641373Notes

Reaction equation

HRID 1641373 reaction equation
C([O:5][C:6]([CH2:8][C@H:9]([C@H:11]([CH2:13][OH:14])[OH:12])[OH:10])=O)(C)(C)C>C(O)(=O)C>[O:5]=[CH:6][CH2:8][C@H:9]([C@H:11]([CH2:13][OH:14])[OH:12])[OH:10]

Participants

3

Reactant 1

HCID 86636537HCID 86636537, compound

Product 1

HCID 69945272-Deoxy-L-ribose

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Conditions

Temperature
40 °C

Procedure

0.5 kg (2.63 mol) of 1-t-butoxy-2-deoxy-L-ribose was dissolved in 2 liters of 1% acetic acid, and stirred at 40° C. for 5 hours. After completion of the reaction, the solvent was removed by concentration, and the residue was azeotropically distilled with toluene, thus obtaining 2-deoxy-L-ribose, which was then used for the preparation of L-anilide without any purification.

Workup

  1. customAfter completion of the reaction
  2. customthe solvent was removed by concentration
  3. distillationthe residue was azeotropically distilled with toluene, thus obtaining 2-deoxy-L-ribose, which
  4. customwas then used for the preparation of L-anilide without any purification

Sources & evidence

ORD record
ord-3bc59aa9863341d99ac8cd6b1395441a
Source dataset
uspto-grants-2012_02
Patent number
US08114987B2

Reaction notes

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