Chromanone → 4H-1-Benzopyran-4-one, 2,3-dihydro-, oxime

Participants

Reaction Steps

A mixture of sodium acetate (41.53 g, 0.506 mol) in water at 60° C. was combined with a stirred mixture of chroman-4-one (25 g, 0.169 mol) and hydroxylamine hydrochloride (20.0 g, 0.287 mol) in ethanol at 60° C. The resulting mixture was heated at reflux for 90 minutes, cooled and filtered. The crude solid was washed with water to give chroman-4-one oxime (27.9 g, yield 96%), mp. 114-117° C., purity 95%.

Provenance & Evidence