HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzylsuccinic acid → 2-Benzylsuccinic anhydride, DL-
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzylsuccinic acid | HCID 3858 | — |
| Solvent | Trifluoroacetic anhydride | HCID 9845 | — |
| Product | 2-Benzylsuccinic anhydride, DL- | HCID 3830286 | 94% |
Reaction Steps
The commercially available alpha-benzylsuccinic acid 9 (1 g, 4.8 mmol) was refluxed for 1 h in 30 mL trifluoroacetic anhydride. Afterwards, the solvent was removed in vacuo. The crude residue was washed with cold hexane to yield alpha-benzylsuccinic anhydride 10 as a white solid (858.2 mg, 93.95%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08119623B2 |
| Source dataset | uspto-grants-2012_02 |
| ORD ID | ord-12c13cdaca3346ed96eb4345c9d559fd |
| Source note | uspto-grants-2012_02 |