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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 164205Generated: October 27, 2026

Sodium ion → 6-Chloro-2-(2,2-difluoro-ethoxy)-nicotinamide

https://huagongshe.com/reaction/164205

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium ionHCID 923—
ReactantWaterHCID 962—
ReactantDimethylformamideHCID 6228—
Reactant1,2-DimethoxyethaneHCID 8071—
Reactant2,2-Difluoroethan-1-olHCID 136187—
ReactantHydrideHCID 166653—
Reactant2,6-Dichloropyridine-3-carboxamideHCID 22142778—
Product6-Chloro-2-(2,2-difluoro-ethoxy)-nicotinamideHCID 57969008—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (9/10)
ORD IDord-0d7e4a2e5e1d46a098bfe908f09c4a50
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (9/10)