Acetaldehyde → HCID 57831007, compound

Participants

Reaction Steps

Substituting isobutyraldehyde for acetaldehyde in Step 2. MP=148-150 C, (M+H)+=276. 7-(2,2-Dimethyl-propionyl)-5H-pyrrolo[2,3-b]pyrazine-2-carboxylic acid isopropylamide Substituting carbon dioxide for acetaldehyde in Step 2. Then following general procedures described in these Examples, using isopropylamine and continuing with Step 3. MP=206-208 C, (M+H)+=289. 1-(2-Acetyl-5H-pyrrolo[2,3-b]pyrazin-7-yl)-2,2-dimethyl-propan-1-one. The product of Step 3 was treated with Dess-Martin periodinane, following general procedures described in these Examples. MP=221-223 C, (M+H)+=246.

Provenance & Evidence