Triacetoxyperiodinane → HCID 44200071, compound

HRID 1642079Notes

Reaction equation

[OH:1][CH:2]([C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][C:19]=1[CH3:24])[C:3]1[N:4]=[C:5]2[C:11]([C:12](=[O:17])[C:13]([CH3:16])([CH3:15])[CH3:14])=[CH:10][NH:9][C:6]2=[N:7][CH:8]=1.CC(OI1(OC(C)=O)(OC(C)=O)OC(=O)C2C=CC=CC1=2)=O>>[CH3:14][C:13]([CH3:16])([CH3:15])[C:12]([C:11]1[C:5]2[C:6](=[N:7][CH:8]=[C:3]([C:2](=[O:1])[C:18]3[CH:23]=[CH:22][CH:21]=[CH:20][C:19]=3[CH3:24])[N:4]=2)[NH:9][CH:10]=1)=[O:17]

Participants

Reactant 2

HCID 159087Triacetoxyperiodinane

HCID 57830995HCID 57830995, compound

Product 1

HCID 44200071HCID 44200071, compound

Procedure

1-[2-(Hydroxy-o-tolyl-methyl)-5H-pyrrolo[2,3-b]pyrazin-7-yl]-2,2-dimethyl-propan-1-one was treated with Dess-Martin periodinane, following general procedures described in these Examples. MP=152-154 C, (M+H)+=322.

Sources & evidence

ORD record: ord-dff5cff40e784a7cae179264015399b3
Source dataset: uspto-grants-2012_02
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08119636B2

Reaction notes

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