Triacetoxyperiodinane → HCID 44200072, compound

HRID 1642080Notes

Reaction equation

[OH:1][CH:2]([C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1)[C:3]1[N:4]=[C:5]2[C:11]([C:12](=[O:17])[C:13]([CH3:16])([CH3:15])[CH3:14])=[CH:10][NH:9][C:6]2=[N:7][CH:8]=1.CC(OI1(OC(C)=O)(OC(C)=O)OC(=O)C2C=CC=CC1=2)=O>>[C:2]([C:3]1[N:4]=[C:5]2[C:11]([C:12](=[O:17])[C:13]([CH3:15])([CH3:14])[CH3:16])=[CH:10][NH:9][C:6]2=[N:7][CH:8]=1)(=[O:1])[C:18]1[CH:19]=[CH:20][CH:21]=[CH:22][CH:23]=1

Participants

Reactant 2

HCID 159087Triacetoxyperiodinane

HCID 57830997HCID 57830997, compound

Product 1

HCID 44200072HCID 44200072, compound

Procedure

1-[2-(Hydroxy-phenyl-methyl)-5H-pyrrolo[2,3-b]pyrazin-7-yl]-2,2-dimethyl-propan-1-one was treated with Dess-Martin periodinane, following general procedures described in these Examples. MP=190-192, (M+H)+=308.

Sources & evidence

ORD record: ord-dafedf40e50748cc83f412f7d01c4e05
Source dataset: uspto-grants-2012_02
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08119636B2

Reaction notes

Loading…