Triacetoxyperiodinane → HCID 44200074, compound

HRID 1642081Notes

Reaction equation

[OH:1][CH:2]([C:18]1[CH:23]=[CH:22][N:21]=[CH:20][CH:19]=1)[C:3]1[N:4]=[C:5]2[C:11]([C:12](=[O:17])[C:13]([CH3:16])([CH3:15])[CH3:14])=[CH:10][NH:9][C:6]2=[N:7][CH:8]=1.CC(OI1(OC(C)=O)(OC(C)=O)OC(=O)C2C=CC=CC1=2)=O>>[CH3:14][C:13]([CH3:16])([CH3:15])[C:12]([C:11]1[C:5]2[C:6](=[N:7][CH:8]=[C:3]([C:2]([C:18]3[CH:19]=[CH:20][N:21]=[CH:22][CH:23]=3)=[O:1])[N:4]=2)[NH:9][CH:10]=1)=[O:17]

Participants

Reactant 2

HCID 159087Triacetoxyperiodinane

HCID 57831002HCID 57831002, compound

Product 1

HCID 44200074HCID 44200074, compound

Procedure

1-[2-(Hydroxy-pyridin-4-yl-methyl)-5H-pyrrolo[2,3-b]pyrazin-7-yl]-2,2-dimethyl-propan-1-one was treated with Dess-Martin periodinane, following general procedures described in these Examples. MP=218-220 C, (M+H)+=309.

Sources & evidence

ORD record: ord-8b866f51184a4c4b8371d349a01620cb
Source dataset: uspto-grants-2012_02
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08119636B2

Reaction notes

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