Bicarbonate Ion → 2-[5-[Hydroxy(pyridin-2-yl)methyl]-2-oxo-1-phenyl-3-pyridinyl]benzonitrile

HRID 164210Notes

Reaction equation

HRID 164210 reaction equation
[BH4-:30].[C:1](#[N:2])[c:3]1[c:4](-[c:9]2[c:10](=[O:29])[n:11](-[c:23]3[cH:24][cH:25][cH:26][cH:27][cH:28]3)[cH:12][c:13]([C:15](=[O:16])[c:17]3[n:18][cH:19][cH:20][cH:21][cH:22]3)[cH:14]2)[cH:5][cH:6][cH:7][cH:8]1.[C:34](=[O:35])([O-:36])[OH:37].[CH3:32][OH:33].[Na+:31].[Na+:38]>>[C:1](#[N:2])[c:3]1[c:4](-[c:9]2[c:10](=[O:29])[n:11](-[c:23]3[cH:24][cH:25][cH:26][cH:27][cH:28]3)[cH:12][c:13]([CH:15]([OH:16])[c:17]3[n:18][cH:19][cH:20][cH:21][cH:22]3)[cH:14]2)[cH:5][cH:6][cH:7][cH:8]1

Participants

6

Reactant 5

HCID 769Bicarbonate IonHCID 887MethanolHCID 923Sodium ion2×HCID 28123BorohydrideHCID 223190923-(2-Cyanophenyl)-5-(2-pyridinecarbonyl)-1-phenyl-1,2-dihydropyridin-2-one

Product 1

HCID 223191772-[5-[Hydroxy(pyridin-2-yl)methyl]-2-oxo-1-phenyl-3-pyridinyl]benzonitrile

Sources & evidence

ORD record
ord-040fffded29144729a83a9b5ae9cc9c8
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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