HuagongsheHuagongshe Chemistry Print Report · For research reference only
Nitrate → 3-Iodo-5-(5-methyl-pyridin-2-yl)-benzoic acid methyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Nitrate | HCID 943 | — |
| Reactant | Diiodomethane | HCID 6346 | — |
| Reactant | Methyl 3-amino-5-(5-methylpyridin-2-yl)benzoate | HCID 57851018 | — |
| Product | 3-Iodo-5-(5-methyl-pyridin-2-yl)-benzoic acid methyl ester | HCID 59432579 | — |
Reaction Steps
3-Amino-5-(5-methyl-pyridin-2-yl)-benzoic acid methyl ester was treated with methylene iodide and isoamy nitrate using the procedure of step 5 of preparation 5, to afford 3-iodo-5-(5-methyl-pyridin-2-yl)-benzoic acid methyl ester, MS (M+H)=353.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08119644B2 |
| Source dataset | uspto-grants-2012_02 |
| ORD ID | ord-7d4c9660e88b437f8b6d4d5dc4102762 |
| Source note | uspto-grants-2012_02 |