Potassium Carbonate → HCID 16124643, compound

Participants

Reaction Conditions

Reaction Steps

Compound 4 (20 mg, 0.081 mmol) was mixed with phenylboronic acid (20 mg, 0.16 mmol) and Tetrakis Pd(0) catalyst (19 mg, 0.016 mmol) in a solution comprising dioxane (3 ml) and a saturated K2CO3 solution (1 ml). The mixture was heated in a microwave reactor at 150° C. for 20 minutes. Purification by HPLC afforded the title compound as a tan solid (4 mg, 22%). 1H NMR (400 MHz, CD3OD) δ 8.39 (s, 1 H) 8.10 (d, J=7.84 Hz, 1 H) 7.67 (m, 2 H), 7.60 (m, 5 H) 7.27 (m, 2 H). [M+H] calc'd for C17H12N2, 245; found 245.

Provenance & Evidence