7-iodo-3,4-dihydropyrido[2,3-b]pyrazin-2(1H)-one → 1-[1-(2-Chloro-3,6-difluorophenyl)ethyl]-7-iodo-3,4-dihydro-1H-pyrido[2,3-b]pyrazin-2-one
Reaction equation
[Br:13][CH:14]([CH3:15])[c:16]1[c:17]([F:24])[cH:18][cH:19][c:20]([F:23])[c:21]1[Cl:22].[I:1][c:2]1[cH:3][c:4]2[c:5]([n:11][cH:12]1)[NH:6][CH2:7][C:8](=[O:10])[NH:9]2>>[I:1][c:2]1[cH:3][c:4]2[c:5]([n:11][cH:12]1)[NH:6][CH2:7][C:8](=[O:10])[N:9]2[CH:14]([CH3:15])[c:16]1[c:17]([F:24])[cH:18][cH:19][c:20]([F:23])[c:21]1[Cl:22]Participants
3
Sources & evidence
- ORD record
- ord-08aeaee964474f80acbdfcb10beb2370
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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