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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1642545Generated: November 1, 2026

5-Amino-3-methyl-9H-pyrido[2,3-b]indole-7-carbonitrile → 5-Amino-3-methyl-9H-pyrido[2,3-b]indole-7-carboxylic acid methyl ester

https://huagongshe.com/reaction/1642545

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-Amino-3-methyl-9H-pyrido[2,3-b]indole-7-carbonitrileHCID 16124311—
Reactant4-(2-Fluoro-5-methyl-pyridin-3-yl)-3,5-dinitro-benzoic acid methyl esterHCID 58880174—
Product5-Amino-3-methyl-9H-pyrido[2,3-b]indole-7-carboxylic acid methyl esterHCID 5888012288%

Reaction Steps

The title compound was prepared in 88% yield from example Compound 128 according to the procedure outlined for the preparation of Compound 124. MS (ES) [m+H] calc'd for C14H13N3O2, 256; found 256.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08119655B2
Source datasetuspto-grants-2012_02
ORD IDord-94dd6f901eb14adf845cbf8ef0a68bdb
Source noteuspto-grants-2012_02