反应详情

The title compound was synthesized from Compound 157 and 2-bromoacetonitrile using an analogous procedure to that outlined in the preparation of Compound 205.1H NMR (400 MHz, CHLOROFORM-d) δ ppm 1.36 (t, J=7.33 Hz, 3 H) 3.22 (q, J=7.33 Hz, 3 H) 5.14 (s, 2 H) 7.31-7.37 (m, 2 H) 7.82 (t, J=7.71 Hz, 1 H) 7.91 (d, J=7.83 Hz, 1 H) 8.09 (d, J=7.83 Hz, 1 H) 8.11-8.15 (m, 2 H) 8.22 (s, 1 H) 14.04 (br. s., 1 H) [M+H] calc'd for C22H19N3O3S, 406; found, 406.