反应详情

The title compound was prepared from Compound 218 by using an analogous procedure to that outlined in the preparation of Compound 215. 1H NMR (400 MHz, Methanol-d4) δ 8.45 (s, 1 H) 8.06 (m, 1 H) 8.01 (m, 2 H) 7.87 (t, J=8.0 Hz, 1 H) 7.63 (s, 1 H) 7.23 (d, J=8.32 Hz, 1 H) 7.16 (d, J=8.32 Hz, 1 H) 4.34 (t, J=6.32 Hz, 2 H) 3.72 (t, J=6.32 Hz, 2 H) 3.43 (q, J=7.32 Hz, 2 H) 2.02 (m, 2 H) 1.18 (t, J=7.32 Hz, 3 H). [M+H] calc'd for C22H22ClN2O4S, 445; found, 445.