Methyl Anthranilate → Methyl 2-[(methylsulfonyl)amino]benzoate

HRID 1642617Notes

Reaction equation

[CH3:1][O:2][C:3](=[O:11])[C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=1[NH2:10].[CH3:12][S:13](Cl)(=[O:15])=[O:14]>>[CH3:1][O:2][C:3](=[O:11])[C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=1[NH:10][S:13]([CH3:12])(=[O:15])=[O:14]

Participants

Reactant 2

HCID 8635Methyl Anthranilate

HCID 31297Methanesulfonyl chloride

Product 1

HCID 669032Methyl 2-[(methylsulfonyl)amino]benzoate

Procedure

2-Methanesulfonylaminobenzoic acid methyl ester is prepared according to the general procedure outlined in Example 4, Step B, using 2-aminobenzoic acid methyl ester and methanesulfonyl chloride.

Sources & evidence

ORD record: ord-38aa850436ff47a88f72e685cce59553
Source dataset: uspto-grants-2012_02
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08119666B2

Reaction notes

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