4-(2-Chloroethyl)morpholine → HCID 74387730, compound

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Reaction Steps

The title compound was prepared using 4-[4-(2,4-Dioxo-thiazolidin-5-ylidenemethyl)-2-fluoro-phenoxy]-3-trifluoromethyl-benzonitrile and 4-(2-Chloro-ethyl)-morpholine as described in Example 1. 1H NMR (400 Hz, CDCl3) δ8.01 (s, 1H), 7.83 (s, 1H), 7.74 (dd, 1H), 7.34 (m, 3H), 6.91 (d, 1H), 3.92 (t, 2H), 3.69 (bt, 2H), 2.69 (bt, 2H), 2.57 (bs, 2H); LC/MS (m/z) [M+1]+ 522.2 (calculated for C24H20F4N3O4S, 522.49).

Provenance & Evidence