HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cyclopentanecarbonyl chloride → Ethyl 1-(cyclopentylcarbonyl)-5-(4-ethylphenyl)piperidine-3-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cyclopentanecarbonyl chloride | HCID 78284 | — |
| Reactant | Ethyl 5-(4-ethylphenyl)piperidine-3-carboxylate | HCID 58002384 | — |
| Product | Ethyl 1-(cyclopentylcarbonyl)-5-(4-ethylphenyl)piperidine-3-carboxylate | HCID 58002263 | — |
Reaction Steps
5.2 g (14.0 mmol) of ethyl 5-(4-ethylphenyl)piperidine-3-carboxylate and 2.1 g (2.1 mmol, 1.2 eq.) of cyclopentanecarbonyl chloride were reacted according to the General Method 3A. Yield: 4.8 g (96% of theory)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08119663B2 |
| Source dataset | uspto-grants-2012_02 |
| ORD ID | ord-d3a1300ec647410a9e4007e0da38b2ca |
| Source note | uspto-grants-2012_02 |