HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Morpholinecarbonyl chloride → Methyl 5-(4-ethylphenyl)-1-(morpholin-4-ylcarbonyl)piperidine-3-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Morpholinecarbonyl chloride | HCID 84810 | — |
| Reactant | Methyl 5-(4-ethylphenyl)piperidine-3-carboxylate | HCID 58002552 | — |
| Product | Methyl 5-(4-ethylphenyl)-1-(morpholin-4-ylcarbonyl)piperidine-3-carboxylate | HCID 58002196 | — |
Reaction Steps
6.2 g (22.6 mmol) of methyl 5-(4-ethylphenyl)piperidine-3-carboxylate and 4.4 g (29.4 mmol, 1.3 eq.) of morpholine-4-carbonyl chloride were reacted according to the General Method 3A. Yield: 7.9 g (97% of theory)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08119663B2 |
| Source dataset | uspto-grants-2012_02 |
| ORD ID | ord-548bca9db3e6486686a111e3c835c7bb |
| Source note | uspto-grants-2012_02 |