Potassium tert-butoxide → HCID 58002436, compound

HRID 1642825Notes

Reaction equation

HRID 1642825 reaction equation
[CH3:1][O:2][CH2:3][CH2:4][NH:5][C:6]([N:8]1[CH2:13][CH:12]([C:14]2[CH:19]=[CH:18][C:17]([C:20]([F:23])([F:22])[F:21])=[CH:16][CH:15]=2)[CH2:11][CH:10]([C:24]([O:26]C)=[O:25])[CH2:9]1)=[O:7].CC(C)([O-])C.[K+]>>[CH3:1][O:2][CH2:3][CH2:4][NH:5][C:6]([N:8]1[CH2:13][CH:12]([C:14]2[CH:19]=[CH:18][C:17]([C:20]([F:21])([F:22])[F:23])=[CH:16][CH:15]=2)[CH2:11][CH:10]([C:24]([OH:26])=[O:25])[CH2:9]1)=[O:7]

Participants

3

Reactant 2

HCID 23665647Potassium tert-butoxideHCID 58002335HCID 58002335, compound

Product 1

HCID 58002436HCID 58002436, compound

Procedure

2.94 g (7.57 mmol) of the compound from Example 104A and 8.49 g (75.70 mmol) of potassium tert-butoxide were reacted according to the General Method 9A. Yield: 2.46 g (80% of theory, 92% pure)

Sources & evidence

ORD record
ord-bf80908025bb42f8804d76082e7ddf8f
Source dataset
uspto-grants-2012_02
Patent number
US08119663B2

Reaction notes

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