Potassium tert-butoxide → HCID 58002525, compound

HRID 1642828Notes

Reaction equation

HRID 1642828 reaction equation
[OH:1][CH:2]1[CH2:5][N:4]([C:6]([N:8]2[CH2:13][CH:12]([C:14]3[CH:19]=[CH:18][C:17]([O:20][C:21]([F:24])([F:23])[F:22])=[CH:16][CH:15]=3)[CH2:11][CH:10]([C:25]([O:27]C)=[O:26])[CH2:9]2)=[O:7])[CH2:3]1.CC(C)([O-])C.[K+]>>[OH:1][CH:2]1[CH2:3][N:4]([C:6]([N:8]2[CH2:13][CH:12]([C:14]3[CH:15]=[CH:16][C:17]([O:20][C:21]([F:22])([F:24])[F:23])=[CH:18][CH:19]=3)[CH2:11][CH:10]([C:25]([OH:27])=[O:26])[CH2:9]2)=[O:7])[CH2:5]1

Participants

3

Reactant 2

HCID 23665647Potassium tert-butoxideHCID 58002216HCID 58002216, compound

Product 1

HCID 58002525HCID 58002525, compound

Procedure

700 mg (1.43 mmol) of the compound from Example 109A and 1.61 g (14.3 mmol) of potassium tert-butoxide were reacted according to the General Method 9A. Yield: 700 g (99% of theory, 84% pure)

Sources & evidence

ORD record
ord-f082428632cb497da015e73097ca9248
Source dataset
uspto-grants-2012_02
Patent number
US08119663B2

Reaction notes

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