Potassium tert-butoxide → HCID 58002371, compound

HRID 1642830Notes

Reaction equation

HRID 1642830 reaction equation
[C:1]([O:5][C:6]([NH:8][CH:9]1[CH2:14][CH2:13][N:12]([C:15]([N:17]2[CH2:22][CH:21]([C:23]3[CH:28]=[CH:27][C:26]([O:29][C:30]([F:33])([F:32])[F:31])=[CH:25][CH:24]=3)[CH2:20][CH:19]([C:34]([O:36]C)=[O:35])[CH2:18]2)=[O:16])[CH2:11][CH2:10]1)=[O:7])([CH3:4])([CH3:3])[CH3:2].CC(C)([O-])C.[K+]>>[C:1]([O:5][C:6]([NH:8][CH:9]1[CH2:14][CH2:13][N:12]([C:15]([N:17]2[CH2:22][CH:21]([C:23]3[CH:24]=[CH:25][C:26]([O:29][C:30]([F:32])([F:33])[F:31])=[CH:27][CH:28]=3)[CH2:20][CH:19]([C:34]([OH:36])=[O:35])[CH2:18]2)=[O:16])[CH2:11][CH2:10]1)=[O:7])([CH3:4])([CH3:2])[CH3:3]

Participants

3

Reactant 2

HCID 23665647Potassium tert-butoxideHCID 58002160HCID 58002160, compound

Product 1

HCID 58002371HCID 58002371, compound

Procedure

785 mg (1.48 mmol) of the compound from Example 113A and 1.66 g (14.8 mmol) of potassium tert-butoxide were reacted according to the General Method 9A. Yield: 740 mg (97% of theory).

Sources & evidence

ORD record
ord-32b0fddc87764f9b96b6efda7370169f
Source dataset
uspto-grants-2012_02
Patent number
US08119663B2

Reaction notes

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