Methyl 5-bromopyridine-3-carboxylate → HCID 58002548, compound

HRID 1642836Notes

Reaction equation

HRID 1642836 reaction equation
Br[C:2]1[CH:3]=[N:4][CH:5]=[C:6]([CH:11]=1)[C:7]([O:9][CH3:10])=[O:8].[CH3:12][C:13]1[CH:14]=[C:15](B(O)O)[CH:16]=[CH:17][C:18]=1[CH3:19]>>[CH3:12][C:13]1[CH:14]=[C:15]([C:2]2[CH:11]=[C:6]([C:7]([O:9][CH3:10])=[O:8])[CH:5]=[N:4][CH:3]=2)[CH:16]=[CH:17][C:18]=1[CH3:19]

Participants

3

Reactant 2

HCID 699336Methyl 5-bromopyridine-3-carboxylateHCID 27343483,4-Dimethylphenylboronic acid

Product 1

HCID 58002548HCID 58002548, compound

Procedure

11.0 g (50.1 mmol) of methyl 5-bromonicotinate and 7.7 g (50.1 mmol) of 3,4-dimethylphenylboronic acid were reacted according to the General Method 1A. Yield: 4.0 g (31% of theory)

Sources & evidence

ORD record
ord-1235b25bb011479ba9027fb68d7e0361
Source dataset
uspto-grants-2012_02
Patent number
US08119663B2

Reaction notes

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