Trifluoroacetic acid → HCID 58002434, compound

Participants

Reaction Steps

185 mg (0.41 mmol) of the compound from Example 174A were initially charged in 25 ml of dichloromethane and, at RT, reacted with 0.32 ml (466 mg, 4.08 mmol) of trifluoroacetic acid. The reaction mixture was stirred at RT for 16 h and then concentrated under reduced pressure. The residue was taken up in ethyl acetate, washed with saturated aqueous sodium bicarbonate solution, dried over sodium sulphate, filtered and concentrated under reduced pressure. Yield: 126 mg (87% of theory)

Provenance & Evidence