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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1642878Generated: November 1, 2026

2,4-Difluorobenzamidoxime → HCID 58002222, compound

https://huagongshe.com/reaction/1642878

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,4-DifluorobenzamidoximeHCID 2823825—
Reactant5-(4-Ethylphenyl)-1-(morpholin-4-ylcarbonyl)piperidine-3-carboxylic acidHCID 58002225—
ProductHCID 58002222HCID 58002222—

Reaction Steps

69 mg (0.20 mmol) of 5-(4-ethylphenyl)-1-(morpholin-4-ylcarbonyl)piperidine-3-carboxylic acid (Example 38A) and 38 mg (0.22 mmol, 1.1 eq.) of 2,4-difluoro-N′-hydroxybenzenecarboximidamide were reacted according to the General Method 1. Yield: 47 mg (47% of theory)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08119663B2
Source datasetuspto-grants-2012_02
ORD IDord-8c033585c99d47af92c88264079ae535
Source noteuspto-grants-2012_02