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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1642895Generated: October 31, 2026

N'-hydroxy-2-phenylethanimidamide → HCID 58002642, compound

https://huagongshe.com/reaction/1642895

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN'-hydroxy-2-phenylethanimidamideHCID 2731007—
Reactant1-(Morpholin-4-ylcarbonyl)-5-[4-(trifluoromethoxy)phenyl]piperidine-3-carboxylic acidHCID 58002500—
ProductHCID 58002642HCID 58002642—

Reaction Steps

80 mg (0.20 mmol) of 1-(morpholin-4-ylcarbonyl)-5-[4-(trifluoromethoxy)phenyl]piperidine-3-carboxylic acid (Example 44A) and 33 mg (0.22 mmol, 1.1 eq.) of N′-hydroxy-2-phenylethanimidamide were reacted according to the General Method 1. Yield: 46 mg (44% of theory)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08119663B2
Source datasetuspto-grants-2012_02
ORD IDord-e582fd6bf20b46489ca8407936d5231a
Source noteuspto-grants-2012_02