HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(4-Fluoro-phenyl)-N-hydroxy-acetamidine → HCID 58002599, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(4-Fluoro-phenyl)-N-hydroxy-acetamidine | HCID 3307868 | — |
| Reactant | 1-(Cyclopentylcarbonyl)-5-(4-ethylphenyl)piperidine-3-carboxylic acid | HCID 46164685 | — |
| Product | HCID 58002599 | HCID 58002599 | — |
Reaction Steps
66 mg (0.20 mmol) of 1-(cyclopentylcarbonyl)-5-(4-ethylphenyl)piperidine-3-carboxylic acid (Example 7A) and 37 mg (0.22 mmol, 1.1 eq.) of 2-(4-fluorophenyl)-N′-hydroxyethanimidamide were reacted according to the General Method 1. Yield: 22 mg (24% of theory)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08119663B2 |
| Source dataset | uspto-grants-2012_02 |
| ORD ID | ord-8b02017043c4447e94fcff05803ae545 |
| Source note | uspto-grants-2012_02 |