2-(4-chlorophenyl)-N'-hydroxyethanimidamide → 4-({3-[3-(4-Chlorobenzyl)-1,2,4-oxadiazol-5-yl]-5-(4-ethylphenyl)piperidin-1-yl}carbonyl)-morpholine

Participants

Reaction Steps

69 mg (0.20 mmol) of 5-(4-ethylphenyl)-1-(morpholin-4-ylcarbonyl)piperidine-3-carboxylic acid (Example 38A) and 41 mg (0.22 mmol, 1.1 eq.) of 2-(4-chlorophenyl)-N′-hydroxyethanimidamide were reacted according to the General Method 1. Yield: 62 mg (63% of theory)

Provenance & Evidence