HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(Morpholin-4-ylcarbonyl)-5-[4-(trifluoromethoxy)phenyl]piperidine-3-carboxylic acid → HCID 58002520, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(Morpholin-4-ylcarbonyl)-5-[4-(trifluoromethoxy)phenyl]piperidine-3-carboxylic acid | HCID 58002500 | — |
| Reactant | HCID 131729451 | HCID 131729451 | — |
| Product | HCID 58002520 | HCID 58002520 | — |
Reaction Steps
161 mg (0.40 mmol) of 1-(morpholin-4-ylcarbonyl)-5-[4-(trifluoromethoxy)phenyl]piperidine-3-carboxylic acid (Example 44A) and 83 mg (0.44 mmol, 1.1 eq.) of tert-butyl[(2-amino-2-(hydroxyimino)ethyl]carbamate were reacted according to the General Method 1. Yield: 127 mg (57% of theory)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08119663B2 |
| Source dataset | uspto-grants-2012_02 |
| ORD ID | ord-e6fb84b56f3249f08fa6c6444e7c8a78 |
| Source note | uspto-grants-2012_02 |