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HRID1642932

反应详情

EQUATION

反应方程式

HRID 1642932 的结构方程式

REACTANTS

反应物

2
结构：CC(C)(C)C(=O)CBr
HCID21642

1-Bromopinacolone

C6H11BrO

结构：NC(=S)C1CC(c2ccc(C(F)(F)F)cc2)CN(C(=O)N2CCOCC2)C1
HCID58002319

未命名化合物

PRODUCTS

生成物

1
结构：CC(C)(C)c1csc(C2CC(c3ccc(C(F)(F)F)cc3)CN(C(=O)N3CCOCC3)C2)n1
HCID58002405

未命名化合物

PROCEDURE

实验过程

100 mg (0.224 mmol) of 1-(morpholin-4-ylcarbonyl)-5-[4-(trifluoromethyl)phenyl]piperidine-3-carbothioamide (Example 53A) and 48 mg (0.269 mmol) of 1-bromo-3,3-dimethylbutan-2-one were reacted according to the General Method 3. Yield: 19 mg (17% of theory)