Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1642955Generated: November 1, 2026

874880-59-8 → HCID 58002125, compound

https://huagongshe.com/reaction/1642955

Reaction equation

Participants

RoleNameHCIDCharge
Reactant874880-59-8HCID 4186362—
Reactant1-(Morpholin-4-ylcarbonyl)-5-[4-(trifluoromethoxy)phenyl]piperidine-3-carboxylic acidHCID 58002500—
ProductHCID 58002125HCID 58002125—

Reaction Steps

80 mg (0.20 mmol) of 1-(morpholin-4-ylcarbonyl)-5-[4-(trifluoromethoxy)phenyl]piperidine-3-carboxylic acid (Example 44A) and 38 mg (0.22 mmol, 1.1 eq.) of 3,5-difluoro-N′-hydroxybenzenecarboximidamide were reacted according to the General Method 1. Yield: 75 mg (68% of theory)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08119663B2
Source datasetuspto-grants-2012_02
ORD IDord-c96164731a2845b3bca517a3ed896bf5
Source noteuspto-grants-2012_02